Covaxin Vs Covishield which is better

 Introduction

        Covid outbreak continue in the world with millions of deaths across the world.  Now World Health Organization (WHO)  and all countries looking forward Covid vaccination to protect the people from Corona Virus.  Vaccines train our immunity system to create proteins which fight with virus, known as antibodies.  Indian Government also started vaccination on January 16, 2021.  Recently on June 7, prime minister Narendra Modi announced free vaccination for all citizens of India.

Major Covid vaccines in India  

    In India there are two major Covid-19 vaccines, one Covaxin developed by Bharat Biotech, and the other Covishield developed by Oxford-AstraZenika and is being manufactured by Serum Institute of India.  Recently Indian Government approved Sputnik-V, and this vaccine is developed by the Gamaleya Research Institute of Epidemiology and Microbiology Russia.  In India Sputnic-V is marketed by Hyderabad based pharma company Dr Reddy's Lab.  But Covishield & Covaxin are the primary vaccines being vaccinated in India.

Covaxin Vs Covishield

1) Development of Vaccines 

Covaxine is an inactivated viral vaccine. And this vaccine is developed with the Whole-Virion Inactivated Vero Cell derived platform technology. They contains dead virus which can not infect a person, but still instruct the immune system to increase a defense mechanism against the active virus.

Covishield vaccine is made from a weakened form of corona cold virus generally known as an Adenovirus from Chimpanzees.  And this virus has been modified to look more like Corona virus.th

2) How these Vaccines work

When the vaccines are injected into a patient and they improve the immunity system to develop antibodies and trains to attack any type of Corona virus infections.

Once a person vaccinated with Covaxin, the immune system start respond to an infection of  live Coronavirus. Cells starts produce antibodies that stick to invaders.  Antibodies target spike protein and prevent the virus from entering cells.  Other kinds of Antibodies block the virus in other way.

When Covishield is injected the trough bloodstream, it does not cause any infection but improves the immune system to produce antibodies to tackle with corona virus.

3) Doses

Covaxin: 2 doses (4 weeks gap between 1st & 2nd dose)

Covishield: 2 doses (At least 84 days or 12 to 16 weeks of gap between 1st & 2nd dose)

4) Which is better Covaxin or Covishield?

Many surveys were held to decide which vaccine is effective, but all these confusing.  Some surveys conveying that covaxin is effective and showing its result as 90-95%, where as covishield  above 70%.  And some other surveys conveying Covishield is effective 95%, where as covaxin above 70%.

5) Side effects of Covid-19 Vaccines

Some of the side effects are there with these vaccines.  

After vaccinated with covaxin it will be painful at the injected place on the body.  Some swelling and redness also appear at the spot.  Some also feel weakness and dizziness, some rashes also appear through out the body, likely to increase heartbeat.  In few members swelling of throat, difficulty in breathing, allergies, vomiting, uneasiness, nausea, fever with headache, body pains, pain of injected arm.  These are the common effects.  

Covishield also causes pain at the spot where injected.  Some may have headache, joint pains and body pains, feeling of fever, feeling of weakness, itching at the injected spot, swelling & redness at the spot,  vomiting sensation, body warm, dizziness etc will appear.

But up to now no clear information has been given. So far no bad effects by the vaccines have been revealed.

 

Conclusion

World Health Organization (WHO) declared that the outbreak of Covid-19 is continuing.  And the pandemic already effected every corner of the world.   Effected global economy.  Many people lost their loving persons and life.  In this pandemic situation Vaccination is the only way to face Covid-19.  WHO & Governments around the world believing that natural immunity would not sufficient to bring normal conditions Vaccination is only the way.         

  

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